However, a significant development has occurred on tribal lands. The Eastern Band of Cherokee Indians (EBCI) has legalized both medical and adult-use cannabis within the Qualla Boundary, marking the first location in North Carolina where cannabis is legal for recreational use. Their medical program and dispensary launched in April 2024, followed by adult-use sales in September 2024 for both tribal members and other adults 21 or older. This unique situation presents an interesting dynamic for the state's burgeoning cannabis industry. Additionally, businesses focused on legal hemp and CBD products are already operating across cities like Matthews, Charlotte, Raleigh, Greensboro, and Durham.

The ongoing legislative discussions for a statewide medical cannabis program indicate a potential for future growth and opportunities for dispensary investment opportunities in North Carolina. For entrepreneurs looking to enter the cannabis market, whether through existing CBD businesses, future medical dispensaries, or real estate suited for cannabis operations, CannaMLS is the number one place to find cannabis businesses and cannabis real estate for sale in North Carolina. Explore listings for potential cannabis dispensary for sale, marijuana business for sale, or other cannabis business for sale opportunities as the state's regulations continue to develop.