Oklahoma's cannabis market has been one of the most dynamic in the nation since voters approved medical marijuana in June 2018 through State Question 788. The state quickly established an accessible medical cannabis program, making it a robust environment for cannabis businesses. While adult-use cannabis remains illegal, the medical market has fostered a significant industry.

For entrepreneurs and established companies looking for cannabis manufacturing businesses for sale, Oklahoma presents a unique landscape. The Oklahoma Medical Marijuana Authority (OMMA) oversees this evolving market, which has recently undergone a period of consolidation. This "reckoning" has seen thousands of cannabis businesses, including processors, exit the market due to stricter enforcement and increased compliance demands, as well as an ongoing moratorium on new licenses until at least August 2026. This creates prime opportunities to acquire existing, licensed cannabis processors in cities like Oklahoma City, Tulsa, and Norman.