While South Carolina has seen legislative efforts to introduce a regulated medical cannabis program, the sale of cannabis through traditional dispensaries, for both recreational and broad medical use, remains illegal under current state law. The state currently only permits the use of low-THC CBD oil for qualifying patients with severe epilepsy, a provision enacted in 2014.

Prospective cannabis entrepreneurs seeking marijuana dispensary for sale or cannabis dispensary for sale in South Carolina should be aware that a legal framework for such businesses does not yet exist. However, the landscape is evolving, with ongoing attempts to pass legislation like the South Carolina Compassionate Care Act, which, if enacted, would establish a regulated medical cannabis program including therapeutic cannabis pharmacies in cities such as Columbia, Charleston, and Greenville.